The recommended dosage is ONE application nightly to the skin of each upper eyelid margin at the base of the eyelashes only. Use of Careprost more than once a day will NOT increase the rate of growth of eyelashes.
  1. Start by ensuring your face is clean, makeup and contact lenses are removed. Contact lenses may be reinserted 15 minutes after the application process.
  2. Place one drop of Careprost into the base of the bottle cap, or carefully place one drop on the end of the applicator brush.
  3. Using a clean eyeliner brush, dip into the cap (if used), and then immediately draw the applicator carefully across the skin of the upper eyelid margin at the base of the eyelashes (where the eyelashes meet the skin) going from the inner part of your lash line to the outer part.
  4. Blot-dry any excess solution beyond the eyelid margin.
  5. Repeat for second eyelid margin. In most instances, one drop is sufficient for the margins of both eyes. Use a second drop if necessary. Discard any extra solution and rinse the cap.
  6. Thoroughly rinse the eyeliner brush and allow to air dry.

NOTE: DO NOT APPLY the drops directly in your eye or to the lower lid. If any Careprost solution gets into the eye accidentally, it is not expected to cause harm. The eye should NOT be rinsed.

CAUTION: If you already have an eye infection, eye disease, recent eye surgery or experience a sudden decrease in visual acuity, you should NOT use Careprost solution.


Start Tretinoin treatments with the lowest concentration (unless you have prior experience and know your concentration). Gel is often used for those with oily skin, while those with dry skin prefer the cream. If this is your FIRST time, apply at a rate of every other night for the first two weeks. Skin peeling and mild irritation is expected, however if irritability increases, reduce the usage amount while increasing the time in between application (once every three days). Increase application to every night by the third week, then increasing the strength only if you notice no results after continual nightly usage.
  • The 0.025% concentration is for general skin improvement.
  • The 0.05% concentration is for reducing wrinkles and fine lines.
  • The 0.1% concentration is used widely for the treatment of acne and blackheads and for those needing higher dosage than the 0.05% for exfoliation and collagen rebuilding.
Cleanse your face with a mild cleanser and warm water. Use your fingertips rather than a sponge or washcloth. Blot your face dry with a clean towel. Wait 20 to 30 minutes before applying Tretinoin to your face to make sure your skin is completely dry. Using any kind of tretinoin cream on damp skin can increase your risk of side effects.

Use only a pea-sized amount for your entire face. Spread it evenly. Rub Tretinoin in thoroughly but gently, avoiding sensitive areas such as inside the nose, the lips or in or around the eyes. If Tretinoin accidentally gets on these parts of your face, rinse it off at once.

Be wary of skin sensitivity. An active ingredient in Tretinoin is acid that peels away layers of skin. The peeling process exposes the skin and causes it to burn more easily in the sun. The skin may become dry and itchy during the peeling process. Avoid exposing your face to the sun, wind and cold weather during the first six months you use Tretinoin, especially during the first few weeks of your treatment. Tretinoin makes your skin more susceptible to sunburn, so make sure to use a good sun protection. Use a sunscreen with a factor (SPF) of at least 15. Regardless if you're using Tretinoin to treat wrinkles, the daily use of sunscreen in your foundation or daily moisturizer is "critical" to protecting your skin from more extensive photoaging. Avoid tanning beds and sun lamps.

Tretinoin may contraindicate other topical or skin medications you're using and may be problematic for those with eczema or seborrheic dermatitis. Do not use Tretinoin if you are currently using any medications for your skin or have a history of skin infections or disease. Do not use Retin-A if you are pregnant, attempting to become pregnant or at high risk of pregnancy. Retinoids may cause fetal harm when administered to a pregnant woman. If you are breastfeeding, you can use Tretinoin but with caution as there are no studies relating to the transmission in human breast milk. Tretinoin cream and gel should not be used if you are allergic to any of its ingredients.